An increasing prevalence of hospital acquired infections and foodborne illnesses caused by pathogenic and multidrug resistant bacteria has stimulated a pressing need for benchtop computational methods to rapidly and accurately classify bacteria from genomic sequence data, and based on that, to trace the source of infection.
BacWGSTdb aims to provide a one-stop solution to epidemiological outbreak analysis and pioneer the movement of whole genome sequencing (WGS) from proof-of-concept studies to routine use in the clinical microbiology laboratory. Bench scientists can also use this database as a convenient tool for phylogenetic analysis of bacterial genomes.
2020
BacWGSTdb 2.0 development finished and new website released.
2019
Added bacterial source tracking with cgMLST strategy.
2018
BacWGSTdb 2.0 project launched and 11 new species were incorporated.
2015
BacWGSTdb 1.0 paper was accepted by Nucleic Acids Research.
2015
BacWGSTdb 1.0 development finished and formally online.
2015
BacWGSTdb 1.0 project launched.
Ye Feng, Shengmei Zou, Hangfei Chen, Yunsong Yu, Zhi Ruan. BacWGSTdb 2.0: a one-stop repository for bacterial whole-genome sequence typing and source tracking, Nucleic Acids Research. 2021; 49(D1): D644-D650.
Zhi Ruan, Ye Feng. BacWGSTdb, a database for genotyping and source tracking bacterial pathogens, Nucleic Acids Research. 2016; 44(D1): D682-D687.
Zhi Ruan, Yunsong Yu, Ye Feng. The global dissemination of bacterial infections necessitates the study of reverse genomic epidemiology, Briefings in Bioinformatics. 2020; 21(2): 741-750.